Methods A patient was diagnosed as Darier s disease by pathology and clinical features. PCR and DNA sequencing were used to detect the gene mutation of the family.

方法1例经组织病理结合临床诊断为毛囊角化病，采用聚合酶链反应和DNA测序方法对此家系进行基因突变情况检测。

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First, when a new copy of copia inserts itself into a fly's genetic material, it may cause a deleterious mutation to a previously healthy gene (hence all the copia-related mutations detected by geneticists).

ECONOMIST: Truly selfish genes