Objective To evaluate the functional alternations of canine renal ischemia and reperfusion injury by using MR perfusion-weighted imaging, and to correlate the imaging with the pathologic findings.
目的结合病理对照研究MR灌注成像评价犬肾缺血再灌注损伤后肾功能的变化。
These results suggest that oxygen free radicals may damage the activity of cytochrome oxidase, the reduction of which may play an important role in the injury of renal ischemia and reperfusion.
提示氧自由基可能损害细胞色素氧化酶活性，细胞色素氧化酶活性降低在肾缺血再灌流损伤中可能起重要作用。
Animal ARF can be induced by renal ischemia-reperfusion injury, glycerine, gentamicin and mercuric chloride, and typical acute tubular necrosis can be observed in pathological changes.
肾动脉钳闭引起的肾脏缺血再灌注以及甘油、庆大霉素、氯化汞均可致实验动物急性肾衰竭，病理学上可见典型的急性肾小管坏死。
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