Chiral alcohols are important building blocks for drug synthesis. The asymmetric reduction of carbonyl compounds with biocatalysts is an important method for producing chiral alcohols.
手性醇是药物合成的重要手性砌块,利用生物催化剂不对称还原羰基化合物是手性醇制备的重要方法。
Biocatalytic reduction of the carbonyl groups or the carbon-carbon double bonds of the compounds has been utilized as a method for transforming the prochiral substrate into chiral product.
生物催化的还原反应能使分子内的羰基或碳-碳双键立体选择性的还原,将潜手性底物转化为手性产物,在不对称合成中有着重要的作用。
Moreover, catalytic hydrogenation can be used to the reduction of a variety of organic compounds, such as nitro, carbonyl, amino, aromatic and heteroaromatic compound, hydroxy group and carboxy group.
此外,它除了还原双键以外可以用来还原各种不同的有机化合物,如:硝基、羰基、氨基、芳香族及杂环化合物、羟基、羧基。
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