Is mainly the size effect and solidification, shrinkage, stress and other issues clearly, to avoid or reduce the segregation, iron manhole cover deformation and crack defects.

主要是明显的尺寸效应和凝固、收缩、应力等问题，避免或减少铸铁井盖的成分偏析、变形、开裂等缺陷的产生。

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One unusual effect of the drug is that it appears to reduce the gradual brain shrinkage seen in MS patients over time, says Mundel.

FORBES: From Cicada Fungus To MS Drug: How Big Will Novartis' New Pill Be?