However, many randomized clinical study results contradict with this.

然而许多随机临床研究得出的结果与此相矛盾。

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But those studies had some methodological and study design flaws, which will be avoided in this new, carefully planned and controlled, prospective randomized clinical study.

但是，这些研究在研究方法和研究设计上有一定的缺陷，本次研究将极力避免这样的缺陷，而进行精心策划和控制和前瞻性的临床研究。

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Two randomized controlled trials (RCTs), one before-and-after study and two retrospective reports on clinical efficacy and safety were retrieved, together with 18 pharmacokinetic studies.

检索到与临床功效和安全性相关的两个随机对照试验(rct)、一个前后对照研究、两个回顾性报告，以及18个药物动力学研究。

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For one, the groups noted the analysis is a retrospective study, not a prospective, randomized controlled clinical trial, which many regard as a gold standard for ferreting out safety concerns.

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