Objective: to investigate the factors involved in the release in vitro degree of terbutaline sulphate pulsatile controlled release pellets.

目的考察硫酸特布他林脉冲控释微丸释放度的影响因素。

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Conclusion: the pulsatile release of aspirin can be controlled by selection of disintegrants of the core and changing composition and thickness of the coating film.

结论：通过选择片芯中的崩解剂、调整包衣层组成和厚度，可以用包衣的方法得到不同时间脉冲释药的阿司匹林片剂。

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CONCLUSION:The pulsatile release of ditiazem hydrochloride could be controlled by adjusting the composition of the outer shell materials and the manipulation condition.

结论：通过调整处方和工艺，可以得到体外不同时间脉冲释药的盐酸地尔硫上（艹）下（卓）片剂。

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