Protein kinases and phosphatases play a central role in cellular signaling.

蛋白激酶与蛋白磷酸酶在细胞信号传递中起着重要作用。

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Here, we will review several kinds of protein kinases as potential targets for CVDs and some difficulty in identifying a protein kinase as a putative therapeutic target for CVDs.

在此，我们将总结一些已经能用于心血管疾病的蛋白激酶靶位，以及一些鉴定与心血管疾病有关蛋白激酶假定的治疗靶位的难点。

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Kinases are protein switches that activate other proteins by adding a phosphate group to them via a process called phosphorylation.

激酶是蛋白开关，它们通过一个称为磷酸化的过程将磷酸基团结合到其他蛋白上并激活这些蛋白。

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Kinases can, in many cases, serve as a mechanism for switching a protein on or switching a protein off.

激酶能够,在很多情况下,能够激活一种蛋白或者关闭一种蛋白

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