To find unknown protein-coding genes, annotation pipelines use a combination of ab initio gene prediction and similarity to experimentally confirmed genes or proteins.
为了找出编码蛋白质的基因，注释流程结合了“从头开始的基因预测方法”和“与已知基因相似性比较”这两种方法。
Structurally, a gene is formed by three regions: a regulatory region called the promoter juxtaposed to the coding region containing the protein sequence, and a “3’ tail” sequence.
从结构上来讲，基因包含三个区域：称为启动子的调节区域；与其并列的编码蛋白质的密码子区域；以及3'端尾部序列。
Each one lacked a gene coding for a particular MDR protein.
每种酵母缺乏一种特定的MDR蛋白基因。
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