He has amassed a profound knowledge of eight languages by industry.

他靠勤奋而精通八种语言。

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In order to understand this novel written in classical Chinese, one must have a profound knowledge of archaic Chinese.

想要读懂这本文言小说，必须有扎实的古代汉语功底。

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The students of the major have to possess not only the profound knowledge of physics, but also the ability of medical practice.

医学物理学专业毕业的学生不仅要有深厚的物理学知识，同时还要很强的医学实践能力。

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With decades of profound knowledge of football theory, Parreira was already fully familiar with Mourinho's ideas.

BBC: At what point is a game of football won and lost?

We are prepared for tough times with good risk management and profound knowledge of the markets where we operate.

FORBES: Magazine Article

Within the training museum specialists have obtained profound knowledge of modern museum practices presented by the leading experts in the field, as well as have exchanged their experience in museum activity in their respective countries.

UNESCO: OFFICE IN MOSCOW