She was suffering from physical and mental exhaustion.

她当时已经是精疲力竭。

《牛津词典》

Over-indulgence would lead people to physical and mental exhaustion as over-work did.

过度的放纵常常和过度的工作一样，也会导致人们身心的疲惫。

youdao

Working for prolonged hours can cause physical and mental exhaustion in most cases. It is important to work for definite hours.

超时工作在很多情况下会让身体和精神都过分疲惫，把工作控制在一定时间内很重要。

youdao

The 25-year-old announced in January that he was suffering from "mental and physical" exhaustion and would be taking a sabbatical from cricket.

BBC: Tait returns to Australia squad

Tait, who returned to action earlier this year after taking a break with mental and physical exhaustion in 2008, has played 22 one-day internationals as well as three Tests for Australia.

BBC: Glamorgan sign Australia fast bowler Shaun Tait