Methods:Patients with locally advanced NPC were enrolled into a prospective, dose escalating phase I study.

方法：局部晚期鼻咽癌患者随机进入前瞻性临床I期试验。

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The phase I study clearly showed the low toxicity of the method and the accumulation of the MMS in the target area.

i期临床研究清楚地显示，此种治疗方法是低毒性的，而且MMS能在靶区内积聚。

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Yang JCH, et al. Osimertinib activity in patients (pts) with leptomeningeal (LM) disease from non-small cell lung cancer (NSCLC): updated results from BLOOM, a Phase I study.

osimertinib在非小细胞肺癌（NSCLC）所致软脑脊膜（LM）病患者（pts）中的活性：BLOOM I期研究的更新结果。

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For its part, Merck notes that its BACE inhibitor recently demonstrated a reduction in cerebral spinal fluid, or CSF, a biomarker, in a Phase I study.

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So why does this tiny Phase I pilot study, successful for only four of six women, matter so much?

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The company recently completed enrollment in a Phase I clinical study of MultiStem in heart attack patients, and is midway through a clinical study of MultiStem in leukemia and other cancer patients.

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