A man does what he must — in spite of personal consequences, in spite of obstacles and dangers and pressures — and that is the basis of all human morality.

一个人将个人得失，障碍、危险还有压力抛在脑后，只是做他必须做的，而这便是人类一切道德的基础。

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In spite of your best planning, sometimes a personal support network must be created on the spot.

尽管如此，你做了最好的筹划，有时候，个人援助网络必须临时建立。

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Man does what he must — in spite of personal consequences, in spite of obstacles and dangers and pressures — and that is the basis of all human morality.

无论个人结果怎样，无论要经历多少阻碍，危险和压力，一个人必须做他该做的事情，这是一切人类道德的基础。

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They are constantly cooking up new schemes to promote their notion of personal rectitude, in spite of the damage it does to the party's brand, especially among swinging (in both senses) single women.

ECONOMIST: Lexington

"This decision was not easy because in spite of the personal nature of this debate, its complexity, the medical repercussions and its seriousness, this issue has become polticized to the extent that much of the rhetoric has substantially diminished the potential for real discourse on such an important matter, " Daschle said.

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In spite of all of these personal issues to deal with, he has rejected any talk of retirement.

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