...升高血压和加速心血管病理的基因为主,特别是肾素血管紧张素系统(renin-angiotensin system,RAS);2)诱导基因表达(over-expression):以降低血压有关的基因为靶基因,如心房利钠肽、内皮型一氧化氮等。
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...维普资讯网 》 2007年第27卷第7期 摘 要: 从拟南芥基因组中克隆了热激转录因子(AtHsfA6a),构建了过量表达(over-expression,OE)和反义(antisense,AS)植物表达载体并转化拟南芥,获得了拟南芥纯合转基因株系.
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...维普资讯网 》 2007年第27卷第7期 摘 要: 从拟南芥基因组中克隆了热激转录因子(AtHsfA6a),构建了过量表达(over-expression,OE)和反义(antisense,AS)植物表达载体并转化拟南芥,获得了拟南芥纯合转基因株系.
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Over expression 过表达 ; 过度表达
cdna over-expression library cdna过量表达文库
her- over-expression her2过度表达
genes over expression 基因过度表达
inducible over-expression 诱导表达
functional over-expression 功能性超表达
her-2 over-expression her过度表达
p gene over expression p53基因表达
One of the well-known mechanisms of MDR is over-expression of P-glycoprotein (P-gp).
P-gp的过表达是其主要机制之一。
参考来源 - 超声波逆转人肿瘤多药耐药的体内实验研究It was generally reckoned that hypomethylation of oncogene was a kind of important molecular mechanism that leaded to its over-expression.
目前研究认为,癌基因低甲基化是导致其异常高表达的一种重要分子机制。
参考来源 - cWe have got the regenerated plantlets transformed by RNAi and over-expression vectors of the two genes.10.
并将其进行了RNAi抑制和超表达的转基因,目前已经得到再生苗。
参考来源 - 海岛棉纤维发育相关基因表达谱分析及功能基因的发掘Whether over-expression of enhanced APX ROS scavenge system can improve salt and alkali tolerance of plant or not is worthy of investigating.
盐碱胁迫下过量表达APX强化活性氧解毒系统能否提高植物抗性,是值得研究的问题。
参考来源 - 盐碱胁迫下水稻OsAPX家族基因表达特性差异研究Fifthly,we constructed gene over-expression vector and delivered the gene into Arabidopsis successfully.
五.构建了该基因的过表达载体。
参考来源 - 一个多逆境诱导的水稻钙调素相似基因的克隆、表达及遗传转化分析These results suggested that M-GS1 over-expression enabled the transgenic plants to sustain relatively higher levels of N assimilation and growth under N limited conditions than wild-type plants, and has the potentials in improving plant N use efficiency.
这些结果表明,M-GS1基因的超量表达具有在低N素供应环境下维持转基因植株N素同化利用效率的潜能。
参考来源 - 甜瓜谷氨酰胺合成酶基因的克隆和功能研究Over-expression of Aurora A causes an increase in centrosome number and aneuploidy, leading to the transformation of mammalian cells.
过量表达Aurora A会使中心体的数量增加,产生异倍体,最终导致哺乳动物细胞的转化。
参考来源 - 细胞有丝分裂相关激酶Aurora C的功能研究Mutants iqm3-1 and iqm3-2 inserted T-DNA of IQM3 gene had been found to be loss-of-function and over-expression line,respectively,by RT-PCR analysis. Phenotypic characterization of the mutants indicated that IQM3 gene related with seed germination and cotyledon expansion.
RT-PCR分析表明,IQM3在拟南芥莲座叶、花序叶、茎、花和根中的表达较强,但在荚果中的表达很弱;IQM3基因的T-DNA插入突变体iqm3-1和iqm3-2分别是功能缺失和超表达突变体,对这些突变体的表型分析表明,IQM3基因与种子萌发及幼苗子叶膨大有密切关系。
参考来源 - 拟南芥IQM3基因的表达分析及其突变体的鉴定The successful establishment of the stress-inducible GUS reporter phenotyping system provided convenience for future high-throughput screening of inducers that stimulate over-expression of artemisinin biosynthetic genes.
逆境诱导报告基因表型显示平台的成功建立,为进一步高通量筛选青蒿素合成基因高效表达诱导剂提供了极大方便。
参考来源 - 青蒿素生物合成在天然及人工模拟环境中的转录调控机制研究·2,447,543篇论文数据,部分数据来源于NoteExpress
Conclusion The over-expression of ICAM-1 may be the leading cause to the perihematoma edema formation and ischemic injury.
结论ICAM-1在血肿周围的高表达推测是脑出血后水肿形成和缺血性损伤的主要原因之一。
The analysis revealed over-expression of several proteins related to energy and fat metabolism in the fat cells from obese people.
细胞分析显示肥胖者的脂肪细胞的多种蛋白质的过度表达是由于能量和脂肪代谢。
She is hunched forward over the wheel with a maniacal expression.
她弓身伏在方向盘前,表情像疯了一样。
RT/V this expression becomes Cv dT over T is equal to CvdT/T=-RdV/V minus R dV over V.
这样,or,RT,over,V,bar。,So,now,这个等式就,可以化成。
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