Methods:The methods of opening skull and free falling body was used to cause open cerebral laceration in rats.
方法：采用开颅和自由落体法相结合，造成开放性脑挫裂伤大鼠模型。在Y型水迷路中测定大鼠的记忆力；
Conclusion: the result indicated that Naochuangning had the therapeutic effect on open cerebral laceration in rats.
结论：脑创宁对开放性脑挫裂伤模型大鼠有一定的治疗作用。
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