It's a complex disease and there are so many factors responsible that it's difficult to blame it on one specific issue.

乳腺癌是一种复杂的疾病，有如此多的引发因素，而仅仅只是责备体重这一个因素是很难理解的。

youdao

It is often difficult to reproduce an issue on just one clone.

在仅仅一个副本上重现问题通常非常困难。

youdao

One London traders' representative calls this "the single most difficult issue" in implementing MiFID.

一名伦敦的交易者代表称这是在执行MiFID中遇到的单个最困难的问题。

youdao

In many ways for Aristotle as it is for every student of politics the most serious the most difficult issue one confronts is the problem of faction.

从很多方面看来，无论是对亚里士多德,还是每位政治系的同学而言,最令人最感严肃,与严重的问题,是派系的问题。

耶鲁公开课 - 政治哲学导论课程节选

His father says he knows that the transplant issue is a difficult one for families.

CNN: Boy not allowed to get life-saving transplant in Japan

Trying to answer one issue in isolation can be difficult.

FORBES: Fee-Only Financial Planner: What's the Difference?

"I should make it clear that we always understood that the photographs issue would be a difficult one for the IRA, " he said.

BBC: NEWS | UK | Northern Ireland | 'Arms photo reasonable': Ahern