Aim To design an universal sequence-tagged oligonucleotide probes for spot quality control of oligonucleotide microarrays.
目的设计一种带有通用序列标签的寡核苷酸探针以应用于寡核苷酸芯片点样的质量控制。
Methods Oligonucleotide microarrays consisting of 87 probes representing 87 human cardiovascular disease-related genes were constructed.
方法制备了包含87个心血管疾病相关基因探针的寡核苷酸芯片。
RNA was analyzed using oligonucleotide microarrays, and a wide range of transcripts with altered expression identified, including many dysregulated in carcinomas arising at other sites.
利用基因芯片对其RNA进行分析，发现大量的基因转录发生改变，包括许多其他部位肿瘤中调节异常的情况也有发现。
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