...易发生肥胖,具有肥胖倾向(obesity-prone,OP),有些个体则可维持正常体重及糖、脂代谢,具有肥胖抵抗倾向(obesity-resistant-prone,ORP)。目前对OP、1.1实验动物雄性清洁级SD大鼠43只,适应性饲养一周,高脂饮食饲养。
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Objective To explore the gene expression of hormone sensitive lipase (HSL) and lipoprotein lipase (LPL) between obesity-prone (op) and obesity-resistant (or) rats induced by a high-fat diet.
目的探讨高脂饮食诱导肥胖易感(OP)大鼠和肥胖抵抗(OR)大鼠,激素敏感性脂肪酶(HSL)和脂蛋白脂肪酶(LPL)基因表达的差别。
Conclusions: To make the model of high-fat diet induced obesity-prone and obesity-resistant rats is according with the biochemistry characteristic of high-fat diet in public.
结论:高脂饮食诱导的肥胖易感和肥胖抗性大鼠模型制备成功,其生化特征符合人群高脂饮食致肥胖的特点。
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