The document re-produces extracts from section 5 of ICH Q11 verbatim in black text, and provides subsequent commentary on EU expectations in the form of explanatory notes within grey-shaded boxes.

文件中摘要的ICH Q 11第5部分内容以黑体字表示，相应的欧盟态度的解说以注释形式放在灰色阴影方框中。

youdao

Notes, commentary and annotation of the colloquial words in Jia Xuan Ci Bian Nian Jian Zhu indicate the authors remarkable skill and great effort.

《稼轩词编年笺注》的笺证和编年最见功力，于口语俗词释义也付出艰辛探索。

youdao

The notes clutter up carefully crafted corporate billboards, obscure Web ads and inject hostile commentary into a platform that was supposed to sing a firm's praises.

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