If we do not know the facts, we are in no position to handle such matter.

不了解情况，就无从解决这类问题。

《新英汉大辞典》

No matter how great you think your software is, if it's not what someone wants, how great can it be?

不论您认为您的软件有多么的好，如果他不是人们想要的，那么它能有多杰出？

youdao

If you're not good-looking, no matter how well you sing, you'll not be onstage.

如果你长得不好看，那么不管你怎么唱，你都无法上台。

youdao

In a country the size of western Europe, we can't be everywhere at the same time, and the hotline allows them to call in no matter where they are and to ask usthe information that we can provide -- even if we're not necessarily able to provide the services directly."

VOA: special.2010.05.03

Under non-marginal cuts, you get the full amount of the cut no matter if you work more or not.

FORBES: Mitt Romney Is No Keynesian

In a rare interview, Tepper argued that all asset classes would go higher no matter if the US economy recovers or not (with the possible exception of the US dollar).

FORBES: Why David Tepper Is Only Half Right

That's why discounts are no panacea: People who are inclined to conserve are liable to pass up something not deemed mission-critical no matter if it's 40% off.

FORBES: Magazine Article