Aiming at bad effect of traditional treatment and poor prognosis in hepatocellular carcinoma, gene therapy is becoming a new promising approach and experimental studies in gene therapy are developing rapidly. We conclude several advancements in animal model, new therapeutic gene, carrier system and strategy of delivery in this article, and find the multiple gene therapy mediated by liposome combined with ligand-receptor system via catheter will be used widely.
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Precision medicine will bring more new therapeutic strategies, drug discovery and development, and gene-oriented treatment.
精准医学将会给疾病治疗策略、药物研发和基因治疗带来更多新的可能。
Gene therapy is a new therapeutic tool for the treatment of diverse types of diseases, including cancer, congenital genetic, infectious, cardiovascular and autoimmune diseases.
基因治疗是一种新的治疗手段，可以治疗多种疾病，包括癌症、遗传性疾病、感染性疾病、心血管疾病和自身免疫性疾病。
CONCLUSION: FAK gene silencing promotes the efficacy of chemotherapeutic drug in leukemic cells, indicating that FAK gene silencing might be considered as a new therapeutic strategy for leukemia.
结论：FAK基因沉默能明显增强白血病细胞对化疗药物敏感性，提示FAK基因沉默有望成为白血病治疗的新策略。
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