BACKGROUND: mechanic pressure could cause neurocyte death. Both direct mechanic injury and complex pathophysiological mechanism can induce the pathological changes of axon and neuronal soma.
背景:机械压迫可造成神经细胞死亡,直接的机械性损伤和复杂的病理生理学机制都可导致轴突和神经元胞体的病变。
Thus, the tip of the leading process actively pulls the soma forward during neuronal migration through a myosin II-dependent forward F-actin flow along the leading process.
这项研究表明,迁移神经元中前导突起顶端通过肌球蛋白介导的肌动蛋白纤维流动活跃的拉动胞体向前运动。
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