Lowering this value means that a rule change becomes effective sooner, but it could have a negative performance impact, as the system will poll more often.

减少该值意味着规则变更的时间更加短了，然而这也会产生负面的影响，因为对于系统的查询将变得更加频繁了。

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This may bring to the enterprise some negative effects such as letting capital lie idle, lowering the profit, undermining the morale, disturbing the development plan, affecting the image and so on.

尾盘会给企业带来诸如沉淀资金、降低利润、打击士气、扰乱开发计划、影响企业形象等负面影响。

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Furthermore, hypothalamic dominant-negative Kir6.2 expression or the delivery of the KATP channel blocker glibenclamide abolished the glucose production-lowering effects of OAG.

此外，下丘脑显性负相Kir2的表达或使用KATP通道阻滞剂格列本脲能抵消oag的作用减少葡萄糖生成的作用。

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Low interest rates to stimulate spending in a recession have always had a negative side, namely, the lowering of the return to savers.

FORBES: FOMC Transparency--Translucence Would Be Better

Some researchers now wonder whether Zetia may have subtle, negative effects that counteract its LDL-lowering ability.

FORBES: A Backlash Against Vytorin?

Some academics, most notably former Fed Vice-Chairman Alan Blinder, have suggested that credit availability could be improved by lowering the rate paid on bank reserves held at the Fed to a negative .25 percent.

FORBES: Ben Bernanke's Big Bazooka Factory Of Fed Policy