Low interest rates to stimulate spending in a recession have always had a negative side, namely, the lowering of the return to savers.

FORBES: FOMC Transparency--Translucence Would Be Better

Some researchers now wonder whether Zetia may have subtle, negative effects that counteract its LDL-lowering ability.

FORBES: A Backlash Against Vytorin?

Some academics, most notably former Fed Vice-Chairman Alan Blinder, have suggested that credit availability could be improved by lowering the rate paid on bank reserves held at the Fed to a negative .25 percent.

FORBES: Ben Bernanke's Big Bazooka Factory Of Fed Policy