This study was to evaluate the effect of MTHFR C677T polymorphism on chemosensitivity and toxicity to 5 FU in patients with gastric carcinoma.

本研究旨在观察mthfr基因C677T多态性对预测胃癌患者对5 - FU的敏感性和化疗毒性的影响。

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Results : Detection of MTHFR gene C677T polymorphism was quickly finished by realtime fluorescence quantitative RT - PCR, and the results were proved to be effective by PCR - RFLP.

结果：荧光定量方法可以快速完成MTHFR C677T基因多态性的检测，检测结果得到传统PCR-RFLP方法的证实。

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Objective To explore relationship between methylenetetra hydrofolate reductase (MTHFR) polymorphism and neural tube defects (NTDs)of women in the northern countryside.

目的探讨北方乡村妇女亚甲基四氢叶酸还原酶（MTHFR）基因多态性与神经管畸形的关系。

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