When activated by maturation factors including VEGF, the pre-osteoclasts differentiated into mature osteoclasts and chew up bone tissue, providing the tumor new space to grow.
一旦由包括VEGF在内的促成熟细胞因子活化后，破骨细胞的前体细胞可以分化成为成熟的破骨细胞，破坏骨组织，给肿瘤细胞的生长腾出空间。
Conclusion Mature mouse osteoclasts can be successfully induced and cultured in vitro from macrophages with Ti-alloy particles.
结论钛合金颗粒存在下，成功将小鼠骨髓巨噬细胞体外诱导培养为成熟破骨细胞。
Objective To explore the method of in vitro induction and culture of mature mouse osteoclasts from macrophages with Ti-alloy particles.
目的 探讨钛合金颗粒存在下小鼠巨噬细胞体外诱导培养为成熟破骨细胞的方法。
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