Strong brands should not make radical changes.

强大的品牌不应该进行彻底的改变。

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When you need to see radical results, look to make radical changes in your life.

当你需要看到完全不同的结果时，那就选择彻底改变。

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It looks like you have a chance to make radical changes at a time when you didn't think it was possible.

你似乎有机会做彻底的改变，但你又觉得不可能。

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If we make--If we solve the problem of boredom setting in with progressive memory loss and radical personality changes, maybe boredom won't set in, but it's not anything that I especially want for myself.

如果用持续失忆,和剧烈人格变化来解决无聊的问题，也许不会产生无聊，但那不是我特别想做的事。

耶鲁公开课 - 死亡课程节选

The NPS managers are very senior Marketing Heads in the Business, so they are empowered to make radical changes when needed.

FORBES: Connect

Coleman said baseball's only hope may be to make some radical changes in youth and high school play.

WSJ: As Baseball Season Beings, Kids Are Losing Interest in the National Pastime

Freeverse seemed open to the idea, though it reportedly said ngmoco had no plans to make "radical changes" to the company in the near future.

FORBES: IPhone Game Publisher Ngmoco Raises $25M, Acquires Freeverse