To make a treatment effective, it must be tailored individually to each patient, and can change over time as the patient’s condition changes.

为了实现有效的治疗，必须针对每个病患进行量身定制，并且会随着病人病情的变化而随时间改变。

youdao

I need to restart the test environment server every time to make the changes effective.

每次我都需要重新启动测试环境服务器才能使得改变生效。

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Technology on its own will not bring reform, but it can make changes easier, cheaper and more effective.

技术本身不会带来变革，但它可以使得改变能够更容易、更为廉价和高效。

youdao

Anyone who has a complex diary, important to himself and to others round him, would testify that putting it on a computer is one of the simplest, most efficient and most cost-effective changes one can make.

ECONOMIST: Letters

By no means does this strategy always work, and unexpected events and the dramatic changes in how most banks make money have made it far less effective.

FORBES: Bank Shot, Global Pocket