Regular exercise can make a great difference to you life.

定期锻炼会对你的生活产生巨大影响。

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One false step will make a great difference.

走错一步一切都不同了。

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If you join us, it will make a great difference.

如果你加入我们，情况就会大不一样。

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"The funding would make a great difference to my performance, " he said.

BBC: Funding worries for boxer Barnes

Bush said there are other provisions of the law that have not received as much attention, but would nonetheless make a great difference in the lives of many Americans.

CNN: Bush talks up tax cuts, education

The efforts of industry have the potential to make a great difference, Clinton argued, but will have a limited effect if young people do not realize that these resources are available to them.

CNN: Lauds efforts in California; offers aid to Navajos