high local concentration 局域高浓度
Conclusion: Local high concentration of DMSO can delay axonal degeneration, which indicates that DMSO can be used for adjuvant treatment of neurodegenerative diseases.
结论:局部高浓度的DMSO能够延缓轴突的退行性病变,提示DMSO可能用于神经退行性疾病的辅助治疗。
The sustained-release anticancer drug implantation can achieve high local concentration with reducing systematic toxicity by implanting sustained-release drug into tumor tissue or interstitial tissue.
抗肿瘤药缓释制剂植入肿瘤组织、瘤周组织的间质中或肿瘤切除后的瘤床,达到局部高药物浓度,降低系统毒副反应。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
结论:CHIP腹腔ddp浓度高,血浆峰值较低,以及高温作用,有利于化疗药物在局部对肿瘤细胞发挥作用,减少肾毒性和全身副作用。
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