abstract:A Lipoxygenase inhibitor is a drug that slows down or stops the action of the lipoxygenase enzyme. The term is almost always used to describe an inhibitor of the arachidonate 5-lipoxygenase enzyme, which transforms EFAs into leukotrienes.
Objective toprobe into the effect of zileuton, a special inhibitorof 5-lipoxygenase (5-lox), on theproliferationandapoptosisofpancreatic cancercells in vitro.