Two approaches in structure-based lead design can be distinguished: denovo design and searching three dimensional structures.

基于结构的先导物设计主要有两种途径：全新设计（又称从头设计）和三维数据库搜寻。

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This paper describes the method to increase the lead on a specific lathe and the measures to improve the lead design accuracy.

本文叙述如何在某一特定的车床上加大导程的方法及提高导枉设计精度的措施。

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But up to the 15th century, the lead strips also helped create the design.

但直到15世纪，铅带也助力了设计的创造。

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Perhaps we have pushed lead design to the limits of what can be accomplished with current designs and materials.

FORBES: Robert Hauser, ICD Watchdog, Offers Viewpoint On Riata Controversy At HRS

El Tahany lead his design and development team to create the platform.

FORBES: The Challenges for Developing Innovation in the Middle East

Under the overall authority of the Assistant Director-General, Education Sector, and the direct supervision of the Director of the Division for Planning and Development of Education, the incumbent will lead the design, coordination, execution and evaluation efforts for programme and projects and play a significant role in policy and strategy direction, development and integration, and resource optimization.

UNESCO: Vacancy : Chief of Section (11/5/2011) (# ED 385 - (P5))