Medical studies have proved that cadmium can cause itai-itai disease after it enters human bodies.

医学研究已经证明，镉进入人体后可引起骨痛病。

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In 1931, the cadmium pollution caused by the "Itai Itai disease" began to appear, to the 50's of last century and spread all over japan.

年，镉污染引发的“痛痛病”开始出现，到上世纪50 年代蔓延到全日本。

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In Japan during the late 1960s, an outbreak of itai-itai disease, or "ouch, ouch" disease, was traced back to cadmium after it poisoned people and softened their bones.

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