It is a big change to conventional way of drilling mud circulation.

是常规钻井泥浆循环方式的重大变革。

youdao

It is a big change from the miraculous corporate history of post-war Japan.

对于战后奇迹般的日本产业而言，这将是一场史无前例的剧变。

youdao

But since it is not starting from scratch, such a big change will hurt a lot of people now in pursuit of benefits a generation hence.

但因为并非从头开始，如此巨大的变动在经过一代人后，将会对现在正追求利益的很多人造成伤害。

youdao

"It's a big deal. How big a deal you have to measure piece by piece but clearly it is the first major change in our health care system since nineteen sixty-five so that's a long time coming."

VOA: special.2010.03.27

It is a big change from the miraculous corporate history of post-war Japan.

ECONOMIST: Japanese business

"Like the poll tax, it is a big change being forced through too fast and, like the poll tax, there is not a consensus of support behind it, " he concluded.

BBC: Former ministers condemn council funding bill

The 'bring-your-own-access' model it is using marks a big change from existing services which tie everything to one net account.

BBC: Microsoft and BT ally on broadband