But for people who have a difficult time controlling their movements, this little navigational issue can be a really big problem.

VOA: special.2011.04.18

So hopefully, it was a time issue in terms of looking at the periodic table, because let's have you tell me what are we looking for here?

希望刚才大家出问题的原因,是因为看周期表有时间限制，请大家告诉我,我们在这里找什么？

麻省理工公开课 - 化学原理课程节选

You've got to put more pressure on one side than the other if you want to push that gas through the throttle, right? So this is where the time scale issue comes into play.

如果你想让更多的气体通过节流阀,应该使一边的压强,大于另一边，是吗？所以这就是,时间尺度发挥作用的地方。

麻省理工公开课 - 热力学与动力学课程节选

The Smart Knob promises a smarter, more secure deadbolt lock that lets us issue time-limited unlock codes or give trusted visitors a way in.

ENGADGET: March 16, 2013 4:15 PM EDT

Sports Illustrated Swimsuit Issue time of year.

FORBES: Women And Sports: Swimsuit Models And Racing Queens

It argued that with ballooning health costs, national health insurance was an issue whose time had come.

NPR: Health-Care Plan: A Massachusetts Miracle?