那格列奈(nateglinide) 三、胰岛素增敏剂 (insulin enhancers) • 大多数2型糖尿病患者存在胰岛素抵抗,从而使 insulin不能发挥其正常生理功能。
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Insulin action enhancers 胰岛素增敏剂
The result showed that the effect of 5? % egg lecithin on enhancing sublingual absorption of insulin is better than the other enhancers and it has no irritation.
结果表明,5 %蛋黄卵磷脂促胰岛素经舌下吸收作用较好,且无刺激性。
OBJECTIVE to study the intestinal absorption characteristics of insulin in the presence of absorption enhancers and to determine the advantageous site of intestinal insulin absorption.
目的研究胰岛素和吸收促进剂合用时在肠道各段的吸收特点,寻找促进胰岛素肠道吸收的最佳位置。
CONCLUSION Penetration enhancers can change the fluidity of membrane lipid and the conformation of membrane protein in certain degrees, and increase the sublingual absorption of insulin.
结论渗透促进剂可以不同程度地影响膜脂流动性和膜蛋白构象,提高胰岛素经舌下给药后的降糖效果。
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