Aim to explore the mechanism of the immune tolerance induced by the auto-islets in the intermingled skin grafting.
目的探索混合皮肤移植中，自体皮岛诱发移植免疫耐受的免疫机制。
Objective on the rat model of heterotopic heart transplantation, the mechanism of immune tolerance induced by portal venous injection of donor spleen cells was studied.
目的利用大鼠异位心脏移植模型，探讨门静脉注射供体脾细胞诱导免疫耐受的机制。
Conclusion: Chimerism and immune tolerance can be induced by Cyclophosphmide and when the grafted skin was rejected, the ratio of t cells from BN significantly decreased.
结论：环磷酰胺可诱导嵌合免疫耐受的产生，在嵌合状态下可检测到供鼠来源的T细胞。当移植皮肤被排斥时，供鼠来源T细胞占总t细胞的比例显著降低。
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