hypoxia-induced factor-1 缺氧诱导因子
hypoxia induced factor 1 a 低氧诱导因子
hypoxia induced factor-1 alpha 血管内皮细胞生长因子
This article reviews recent studies on expression and significance of hypoxia-induced factor-1 in gliomas.
本文就缺氧诱导因子- 1在胶质瘤中的表达及意义作一综述。
Hypoxia-induced factor-1 is a transcription factor which is widely studied in recent years. It helps progressing tumors adapt to hypoxia stress and also provides a new clue for tumor therapy.
缺氧诱导因子- 1是近几年研究较多的转录因子，它可使肿瘤在生长侵袭过程中适应缺氧应激，也为肿瘤治疗提供了新思路。
Furthermore, studies suggest that increased activity of this pathway is a contributing factor to hyperglycemia-induced insulin resistance (1, 2).
除此之外，研究表明，该途径的激活是高糖诱导的胰岛素抵抗中的一个作用因素(1,2)。
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