By using improved simplex method and residuals method, a calculation based on the parameters of compartment model of pharmacokinetics is presented.

基于改进的单纯形算法和残数法，对药物动力学房室模型中的有关参数计算进行了研究。

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In order to adapt to the optimization of the complex mechanical products, a new simplex method is presented. Then the simulated annealing algorithm is improved by using the new method.

为了适应复杂机械产品优化设计，提出一种修正的单纯形法，并用来改进模拟退火算法。

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