This study was to explore CHEK2 gene mutation in human breast cancer, and assess the value of assay of Tumor Specific Growth Factor (TSGF), CA15-3, CA125 and CEA in the diagnosis of breast cancer.
本研究探讨CHEK2基因突变与乳腺癌的关系。同时探讨恶性肿瘤特异性生长因子(TSGF)、CA15 - 3、CA125及CEA检测在乳腺癌诊断中的价值。
Conclusion the site specific point mutation system can modify human gene in vitro more accurately. It is useful in the setting up of animal models.
结论体外定点突变系统可以对基因进行精细的修饰，为建立更精确地模拟人类疾病的动物模型打下基础。
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