Conclusion Prenatal exposure to low level lead could promote the GFAP protein and mRNA expression at hippocampal CA1 region,which maybe is one of the molecular mechanisms of lead on learning and memory.
结论妊娠期母体低水平铅暴露可以使仔鼠海马CA1区GFAP蛋白和mRNA表达增加,这可能是铅影响学习记忆的分子机制之一。
参考来源 - 妊娠大鼠低铅暴露对子代海马GFAP表达影响Part I Involvement of (β-adrenoceptors in hippocampal CA1 region in in vivo long-term potentiation and spatial learning in rats Activation of (β-adrenoceptors in area CA1 of the hippocampus facilitates in vitro long-term potentiation (LTP) in this region.
第一部分 大鼠海马CA1区β-受体参与长时程增强和空间 学习在离体海马脑片上,激活CA1区(-肾上腺素能受体(β-受体)易化这一区域突触传递的长时程增强(LTP)。
参考来源 - 海马脑区去甲肾上腺素β·2,447,543篇论文数据,部分数据来源于NoteExpress
METHODS: Extracellular population spikes of the pyramidal cell layer in the hippocampal CA1 region were recorded in vitro.
方法:细胞外记录离体海马脑片CA1区锥体细胞层群体峰电位。
Under the laser confocal microscope, we observed the number of red fluorescence-labeled cells in the cortex and hippocampal CA1 region.
激光共聚焦显微镜下观察皮质区、海马ca 1区红色荧光标记细胞数量。
Objective: To investigate the relation between the astrocyte and the synaptic number or maturity in the hippocampal CA1 region of growth rats.
目的:研究发育期大鼠海马CA 1区星形胶质细胞与突触数量和成熟度的关系。
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