Objective to identify live attenuated hepatitis a (HAV) vaccine virus seed and detect adventitious agents, monoclonal antibody is used to neutralize instead of human and rhesus monkey immune serum.

目的利用单克隆抗体代替常规的人、猴免疫血清进行甲型肝炎减毒活疫苗毒种外源因子检查及鉴别试验。

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Conclusion Anti HAV IgG response of the children who failed to respond to HBV vaccine after injected with the live attenuated HAV vaccine was lower than that of normal children.

结论接种乙肝疫苗免疫失败儿童接种甲肝减毒活疫苗的免疫效果比健康儿童差。

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