Dowtown and suburb has significant difference.

市区、郊区患病率有显著性差异。

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Soil micromorphology has significant difference in different treatment.

不同处理土壤微形态差异明显。

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Two groups of total curative effects has significant difference(P<0.01).

两组总疗效具有显著性差异（P<0.01）；

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Last week's rally, which sent the Dow up nearly 2%, has made a significant difference.

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Monreal has noticed a significant difference in Garcia over the past few years -- not just physically.

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Starting at the same price as the Roku Media Player, it has at least one significant technical difference.

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