The NavmeshQueryFilter is a seemingly minor class, but it has a large impact on navigation.

是一个看起来很小的类，但是它对导航的影响很大。

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The migration of youth from rural area has a large impact on living arrangement of elderly.

农村年轻劳动力外流对老年人的居住安排产生了很大影响。

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The rate of extrusion has a large impact on the quality of the product and should be adjusted accordingly.

挤压比率大大的影响着产品质量，因而需要相应的调整。

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In this nascent age of Social TV metrics, a philosophy about what actually matters in the space has a large impact on results.

FORBES: SpongeBob SquarePants vs. The X Factor: A Social TV Throwdown In Infographics

The city has a very large population of people who are HIV infected and drug prices have a significant impact on its finances, according to AHF, which uses this language in its proposed referendum (which you can read here).

FORBES: Backlash Over New Gilead AIDS Drug Begins

This ideological disconnect has already caused intense fights within the western state legislatures, and is likely to have a large impact on next year's elections.

ECONOMIST: A new Republican heartland