The replacement of primary and permanent teeth is an important part that belongs to the growth and development of animals' teeth and maxillofacial region.

乳恒牙替换是动物牙齿及颌面部生长发育的重要阶段，包含有乳牙根、牙槽骨的吸收、恒牙胚的发育和恒牙萌出等一系列复杂的生理过程。

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Objective To study the expression and significance of Vascular Endothelial Growth Factor(VEGF) in the development of dogs permanent teeth germs.

目的：探讨犬乳恒牙替换过程中血管内皮生长因子（ VEGF）在犬恒牙胚发育中的表达及意义。

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