...化合物在 10 Lmol /L浓度下对低钾诱导的大鼠主动脉条收缩均有不同程 度的抑制作用, 该活性可被钾通道阻滞剂格列苯脲( Glyburide)所逆转, 其中化合物 7a、7c、7d、8a和 8b 的抑制率在 50%以上, 分别为 104%、72%、95%、59%和 51%, 对照药 Emakalim为 128%。
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液相色谱-质谱联用法检测某些中药制剂中的格列本脲-药学-生物谷 关键词：中药制剂；口服降糖药物；格列本脲；液相 色谱 [gap=919]Key words：Traditional Chinese medicine；Antidiabetics；Glyburide；LC／MS
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优降糖（Glyburide）对心肺转流下冠脉搭桥术中尼可地尔（Nicorandil） 血流动力学作 用的影响, 《临床麻醉学杂志》,2005；21（8）：533-534 （第一作...
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Glyburide-d11 格列本脲
Glyburide-d3 格列本脲
Glyburide Related Compound B 格列本脲杂质B
Glyburide Related Compound 格列本脲杂质B
Glyburide And Metformin Hydrochloride 商标名
Glyburide Related Compound A 格列本脲杂质A
micronized glyburide 微粉化格列本脲
Glyburide IMpurity D 优降糖杂质D
Animal experiment showed the DM was of remarkably reduce the blood sugar level of hyperglycemic mice with Adrenaline and Tetraoxypyrimidime inducing hyperglycemia (P<0.001) and return the blood sugar of above experimental diabetes mice to normal level. The DM decreasing blood sugar effection was superior to Phenformin (P<0.02). equal to Glyburide (P>0.05). but didn’t have the glycopenic reaction of GlyburideClinical study showed the notable effective rate of decreasing blood sugar in curative group and control group was 63.3%, 23.3% separately.
实验结果表明：该合剂具有显著降低肾上腺素和四氧嘧啶造模动物的血糖（P＜0.001），使血糖恢复正常，其疗效优于降糖灵即苯乙胍（P＜0.02），类似于优降糖（P＞0.05），且无优降糖的低血糖副反应。
参考来源 - 石斛合剂对糖尿病的临床和实验研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes.
不良妊娠结局与格列本脲与胰岛素在妊娠期糖尿病妇女协会。
Glimepiride, glipizide, glyburide and repaglinide lead to too-low blood sugar more often than other drugs do.
与其他药物相比，格列美脲、格列吡嗪、格列本脲和瑞格列奈更容易导致低血糖。
Objective The clinical effects of maximal dose glyburide therapy in markedly symptomatic patients with NIDDM were further evaluated.
目的通过本项研究进一步评价最大剂量优降糖治疗症状明显的NIDDM患者的临床疗效。
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