If given a push, the topics could be pursued through other negotiating groups, international regimes, or global and regional institutions.

如果有相应的推动因素，其它谈判小组、国际机制或者全球性和区域性机构，也会为解决这些议题作出不懈努力。

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American diplomats have to work with entrepreneurs and activists, use new technological tools such as social media and update the global and regional institutions that have dominated international affairs since World War II, Clinton said.

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Instead of falling apart, Pittsburgh strengthened its core by becoming home to major global financial institutions such as Federated Investors, the aforementioned PNC and the regional headquarters for BNY-Mellon, a move that ultimately sheltered the city from the 2008 recession.

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