Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
Conclusion High expression of VEGF by gene modification can promote the vascularization process of skin substitute, hence improve the grafting result.
结论基因修饰所致VEGF高表达明显促进了移植皮肤替代物的血管化过程，提高了移植物成活率。
Methods The P16 gene modification and PCNA protein expression were detected in 41 brain glioma specimen with different grades and 7 normal brain tissue specimen.
方法检测41例不同级别脑胶质瘤标本和7例正常脑组织P16基因改变和PCNA蛋白表达情况。
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