These knockout procedures are now commonly done in mice and rats, and three researchers earned a Nobel prize in 2007 for developing this method, called "gene targeting".

这种基因敲除程序现在已经被普遍用于小鼠和大鼠，3名研究人员因为发明了这种“基因打靶”技术获得了2007年的诺贝尔奖。

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Gene targeting technology and its application in research of animal model of human disease were briefed in this paper.

本文就基因打靶技术及其在人类疾病动物模型研究中的应用做一介绍。

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Briefly introducing concepts and the primary technical procedure of gene targeting, and systematically introducing selective methods and gene targeting strategies.

简要阐述了基因打靶的概念和基本环节，系统介绍了筛选方法和基因打靶的策略。

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The first practical application of embryonic stem cells was to provide a way for the gene-targeting trick invented by Dr Capecchi and Dr Smithies to be used to produce adult mice lacking particular genes or knockout mice, as they are now called.

ECONOMIST: The 2007 Nobel science prizes

Genasense, which is used in combination with chemotherapy, works by targeting a key "cell suicide" gene called bcl-2 and then inducing cancer cells to kill themselves.

FORBES: Magazine Article