Organophosphates have long worried scientists and regulators because they irreversibly block an enzyme critical to nerve function in both insects and humans.

长久以来，科学家们和监管机构对有机磷酸酯都很担忧。 因为有机磷酸酯会对昆虫和人类的神经活动中一种很重要的酶产生不可逆的阻碍。

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The mutation meant that the enzyme could not function, so serotonin production would be lower than average and, potentially, carriers of the mutation would be more prone to depression.

这种变异意味着酶无法正常发挥作用，因此5 -羟色胺的量会低于正常水平，而且携带这类变异基因的人更有可能患上抑郁症。

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If the acetylcholinesterase continued to function normally, Tawfik concluded that the mutated enzyme had successfully degraded the nerve agent.

如果乙酰胆碱酯酶能够正常工作，那么就意味着新的变异酶成功地降解了神经毒气。

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The function of this enzyme is to hydrolyze triglycerides into free fatty acids, an essential step in the metabolism of fats from consumed food.

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Researchers used x-ray technology to examine the structure of the enzyme, which changes depending on its function.

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Using this data, Adams in 1995 concocted an unusual boron molecule that snuggled into one of the enzyme's active sites and blocked its function.

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