This gene can convert a less toxic drug, 5-fluorocytosine (5-fc), to 5-fu inside the stem cells, and the chemotherapy can then seep out into the tumor, producing a lethal by-stander effect.
该基因可在干细胞中将毒性小的5 -氟胞嘧啶(5 - FC)转变为5 - FU,该化疗药物由干细胞进入肿瘤细胞,产生致死性的旁观者效应。
This is an enzyme that converts a drug called 5-fluorocytosine (5-fc) into an active chemotherapy drug, 5-fluorouracil (5-fu), but only in the immediate vicinity of the stem cell.
胞嘧啶脱氨酶是一种能够将叫做5 -氟胞嘧啶(5 - FC)的药物转化为活跃的化疗药物5 -氟尿嘧啶的酶,但这种情形只发生于干细胞的紧邻。
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