There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.
肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。
Objective: To investigate the expression characteristics of FHIT protEin in breast carcinomas and its relationship with clinicopathological parameters.
目的：探讨FHIT基因蛋白在乳腺癌中的表达特点及其与临床病理参数的关系。
Methods: Expression of FHIT protEIn in breast carcinoma tissues of 62 cases was detected by SP immunohistochemistry.
方法：采用免疫组织化学sp法，检测62例乳腺癌组织中FHIT蛋白的表达情况。
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